Image Source: CBS News
At Lambert High School in suburban Atlanta, a group of innovative teens has turned the tides for Lyme disease research by harnessing cutting-edge CRISPR technology. Their groundbreaking approach aims to revolutionize detection and treatment options for this often-misdiagnosed disease, which affects nearly half a million people annually in the United States.
Building the Future of Lyme Disease Research at Lambert High School
The students, known for their intellect and creativity, participated in the International Genetically Engineered Machine (iGEM) competition in Paris. Their project, which strived to develop more efficient diagnostics for Lyme disease, showcased the potential of synthetic biology in solving real-world health issues.
Led by team captains Sean Lee and Avani Karthik, the students explored a novel way to observe Lyme disease by targeting a specific protein generated by the infection. Existing diagnostic tests often fall short during the early stages of the illness, which can lead to prolonged suffering and irreversible damage.
Innovative Techniques and Breakthroughs
The Lambert team’s idea was to use CRISPR to pinpoint and amplify certain DNA strands that contain this protein. By utilizing a simulated blood serum, they could effectively detect Lyme disease much earlier than current tests allow – within just two days of infection. This is a significant leap from the standard two-week window required by existing methodologies for accurate diagnosis.
In explaining their work, Sean emphasized the challenge, saying, “We did reach out to a bunch of different professors and stakeholders who gave feedback on our project.” They combined academic support with ingenuity, demonstrating profound understanding and commitment to scientific excellence.
Creating a New Approach to Treatment
In addition to improving detection, they also worked on potential treatments. Unlike standard therapies that rely on antibiotics, the Lambert students sought to utilize CRISPR to target and eliminate the bacteria responsible for Lyme disease. This ambitious endeavor included developing sophisticated software to model effective uses of CRISPR in targeting the bacteria.
Their teamwork and relentless persistence secured funding for sophisticated lab equipment that mirrors a college-level environment, propelling them to achieve results that could change the landscape of Lyme disease treatment. This is a testament to their affluent district’s commitment to nurturing talented students.
Teamwork and Recognition on a Global Stage
With their sights set on iGEM, the Lambert High School students faced fierce competition from hundreds of teams, including numerous international entrants. They embraced intense preparation, pulling all-nighters and collaborating on every aspect of their presentation, from coding to designing a website dedicated to their project.
When the competition came around, they excelled, ultimately finishing in the high school top 10, marking them as the only American school with such a distinction. Although the grand prize was awarded to a team from China, the Lambert team celebrated their achievement of winning the category for best software tool, reinforcing their status as pioneers in biotechnology.
The Future Looks Promising
The enthusiasm and spirit of these students illuminate the importance of science education and innovation. Kate Sharer, their biotechnology teacher, stated, “They are so smart that I can’t keep up,” highlighting the unique connections formed between students and educators in this groundbreaking environment. They’ve set an impressive standard, emphasizing the vitality of harnessing young talent for critical challenges such as Lyme disease.
As Lambert High School continues to cultivate future leaders in biotechnology, their project may serve as a beacon of hope not just for Lyme disease sufferers but for potential diagnostics that could apply to a wide range of medical conditions. The works of Sean, Avani, and their peers serve as a powerful reminder of the impact young scientists can have on the world.
FAQs about Lambert High School and Their Lyme Disease Project
What is the main objective of Lambert High School’s project?
The main goal is to develop an innovative method for detecting and treating Lyme disease using CRISPR technology.
How does the Lambert High School project improve Lyme disease diagnostics?
It aims to detect Lyme disease as early as two days after infection, significantly earlier than current tests.
What recognition did Lambert High School receive at the iGEM competition?
The Lambert students finished in the high school top 10 and won the award for best software tool.
Who led the Lambert High School iGEM team?
The team was led by students Sean Lee and Avani Karthik, along with their classmates.
What does this project signify for the future of biotechnology?
The Lambert High School project showcases the potential of youth in biotechnology and emphasizes the need for innovative solutions in health care.
